Micro Solutions / Life Science

Nanopore sequencing PromethION 24

Manufacturing sequencing for large genomes: up to 4.8 TB of data from 24 cells

Product overview

PromethION 24
Oxford Nanopore Technologies
Great Britain
MinION / GridION / PromethION
PromethION 24

Manufacturing sequencing for large genomes: up to 4.8 TB of data from 24 cells

with four GPUs for real-time processing of terabase data

PromethION 24 is a productive platform for large genomes, population projects and high-ultiplex research.

Up to 24 cells run independently or in parallel; a four-GPU computing unit processes terabases of data in real time; and modularity allows for project combinations without necessarily having to be packaged.

1–24 PromethION Flow Cells; typical output of 100–200 GB per cell and 2.4–4.8 TB per device, less than 1–72 h, 20 p.p. readings – more than 4 MB Sequencing unit 590×190×430 mm, 23 kg; computing unit 178×440×470 mm, 26 kg, 4 GPU, 512 GB RAM and 60 TB SSD.

Key figures

1–24

Independent Promethion Flow Cells

up to 4.8 TB

device

4 GPU

data-collection

512GB

RAM

Applications

Sequencing of the human genome and large genomes
Oncological research
Metagenomics
isoform transcriptomics
Single-cell sequencing

Models and configurations

PromethION 24

Product details

PromethION 24

24-cell production platform

Sequencing Unit and Data Acquisition Unit

sequencing and calculation blocks

Scope

1 to 24 independent Promethion Flow Cells without mandatory sample packing
Up to 4.8 TB of data per device when 100–200 GB is released from the cell
Supporting multiple users and projects simultaneously

Calculations

4 NVIDIA Ampere-series GPUs and 1 NVIDIA Turing-series GPUs in the data collection unit
512GB RAM and 60TB SSD (56TB available)
Two 10 Gbps (optics or Ethernet) ports for data transfer

Ready-made scenarios

Comprehensive determination of variants of the human genome – 3 days, up to 24 samples
Accelerated analysis of the human genome in 1 day, up to 8 samples
Hereditary cancer panel on 258 genes – 5 days, up to 72 samples
Isoform transcriptomics: about 80 million readings per sample – 4 days, up to 24 samples

Sequencing

Flow cells	1–24 PromethION Flow Cells
Typical exit	100–200 GB per cell; 2.4–4.8 TB per device
Time to run.	less than 1-72 hours
Length of reading	20 pp to more than 4 MB

Sequencing Unit (Sequencing Unit)

Weight	23 kg
Size (WxVxG)	590×190×430 mm
Maximum power	1 210 W
Power supply	100–240 V AC (50/60 Hz)

Data Acquisition Unit (Data Acquisition Unit)

Weight	26 kg
Size (WxVxG)	178×440×470 mm
GPU	4× NVIDIA Ampere-series + 1× NVIDIA Turing-series
RAM	512GB
Storage	60 TB SSD (56 TB available)
Maximum power	2,640 W
Power supply	200–240 V AC (50/60 Hz)
Network	2×10 Gbps (optics or Ethernet)

S and conditions of operation

OS	Ubuntu Focal 20.04 / Ubuntu Noble 24.04
Operating temperature	+18…+22 °C

Flow cells

PromethION Flow Cell

Cell to run sequencing on PromethION 24

Related equipment types

Promethion flow cells
Systems for nucleic acid isolation
UPS and uninterruptible power systems
Workstations for bioinformatics analysis

Classification

Sequencing and genotyping
Nanopore sequencers (long readings)
Equipment for molecular biology and genetics
Sequencing
Nanopore sequencers (long readings)
PromethION 24