2
BRCA1/BRCA2 gene
Micro Solutions / Life Science
NGS panel BRCAaccuTest PLUS
NGS test of hereditary breast and ovarian cancer: BRCA1 and BRCA2 genes
Product overview
- BRCAaccuTest PLUS
- NGeneBio
- Republic of Korea
- accuTest / accuPanel
- BRCAaccuTest PLUS
NGS test of hereditary breast and ovarian cancer: BRCA1 and BRCA2 genes
for blood samples and FFPE tissue, sequencing on the Illumina MiSeq platform
The BRCAaccuTest PLUS NGS test detects BRCA1 and BRCA2 gene mutations from blood and FFPE tissue samples, helping to assess the risk of hereditary breast and ovarian cancer.
The next-generation sequencing test system identifies pathogenic variants in BRCA1 and BRCA2 genes in genomic DNA from blood or tumor FFPE tissue samples. Sequencing is performed on Illumina MiSeq devices with an average coating of about 200× for germinal and 1,000× for somatic samples. NGeneAnalySys, which forms a clinical report.
The BRCAaccuTest PLUS panel covers the BRCA1 and BRCA2 genes. Diagnostic efficacy was confirmed in a sample of 108 samples - the results are more than 99% matched.
Key figures
CE-IVD
certification
1 000×
somatication
>99%
diagnostic match
Applications
- Hereditary breast cancer
- Hereditary ovarian cancer
- Screening for BRCA1/2 mutations
- Oncogenetics
Models and configurations
- BRCAaccuTest PLUS
precision
- Average sequencing coverage of about 200× for germinal and 1,000× for somatic samples
- Diagnostic match of results confirmed on 108 samples - more than 99%
Clinical application
- Determination of variants in BRCA1 and BRCA2 genes from genomic DNA from blood or FFPE tissue
- The results are used to assess the risk of inherited breast and ovarian cancer
Platform
- Sequencing is performed on Illumina MiSeq instruments
- Compatible with NGeneAnalySys for interpreting options and reporting
Panel
| Genes | BRCA1, BRCA2 |
|---|---|
| Type of sample | genomic DNA from blood or FFPE tissue |
| Average coverage | ~200× (germinal samples); ~1,000× (somatic samples) |
| Clinical validation | 108 samples, diagnostic match over 99% |
Platform and software
| Sequencing | Illumina MiSeq |
|---|---|
| Analysis | NGeneAnalySys |
Certification
| Status | CE-IVD |
|---|
Related equipment types
- Illumina sequencing
- Software for analyzing NGS data
- DNA excretion kits
Related products
- BGI DNBSEQ-E25 — Illumina sequencing
- Xian Tianlong Nucleic acid isolation kits — DNA excretion kits
Classification
- Sequencing and genotyping
- Clinical NGS panels with analysis software
- Equipment for molecular biology and genetics
- Reagents and kits for molecular diagnostics
- Oncological and hereditary panels
- BRCAaccuTest PLUS