300 Hz
speed
Micro Solutions / Life Science
TIMS-MS platform timsultra AIP
Supersensitive TIMS-MS platform for single-cell proteomics at PASEF speeds up to 300 Hz
Product overview
- timsUltra AIP
- Bruker
- Germany
- timsTOF
- timsUltra AIP
Supersensitive TIMS-MS platform for single-cell proteomics at PASEF speeds up to 300 Hz
Athena Ion Processor for more than double signal amplification
An ultrasensitive TIMS-MS platform for single-cell proteomics, immunopeptidomics and plasma analysis.
Athena Ion Processor programmatically focuses informationally significant mass ranges, and CaptiveSpray Ultra 2 enhances ionization transfer and stability. MOMA helps to separate co-eluting isobaric ions by mobility.
PASEF operates at speeds up to 300 Hz with almost 100% ion efficiency, and the manufacturer indicates more than double signal amplification thanks to AIP and support for ICC 2.0 and diagonal-PASEF.
Key figures
×2
signal enhancement
ICC 2.0
ion-control
Applications
- Single-cell proteomics
- Immunopeptidomics
- Plasma analysis
- Deep proteome profiling
Models and configurations
- timsUltra AIP
Product details
timsUltra AIP
TIMS-MS platform with Athena Ion Processor
Sensitivity
- Athena Ion Processor (AIP) programmatically focuses information-relevant mass ranges and provides more than two-fold signal amplification.
- CaptiveSpray Ultra 2 improves ion transfer and ionization stability in low streams
Separation and accuracy
- MOMA separates co-eluting isobaric ions by mobility
- ICC 2.0 monitors ion charge to improve accuracy of quantitative analysis
- Diagonal-PASEF is supported, a mode exclusive to the TIMS platform.
Speed
- PASEF operates at speeds up to 300 Hz with almost 100% ion efficiency.
Technology
| Type of platform | TIMS-MS with Athena Ion Processor (AIP) |
|---|---|
| PASEF speed (MS/MS) | 300 Hz |
| Strengthening the AIP signal | more than 2 times |
| Ion charge control | ICC 2.0 |
Data collection regimes
| Supported regimes | PASEF, diagonal-PASEF |
|---|
Related equipment types
- Nano-HPLC systems
- Proteomics software
- Nitrogen generators
Classification
- Toxicology and omics
- Proteomics
- Analytical instruments for biological samples
- Mass spectrometry
- Q-TOF and ionic mobility (timsTOF): proteomics, metabolomics
- TIMS-MS platform timsultra AIP