TIMSOMNI SIGMA Mass Spectrometer

Product overview

• timsOmni Sigma
• Bruker
• Germany
• timsTOF
• timsOmni Sigma

PASEF-EXD Platform for Structural Biology and Glycoproteomics with Regulated Electron Energy

with Omnitrap and mobility division for PTM analysis and conformation

Highly sensitive multiOmics platform PASEF-EXD for structural biology and glycoproteomics.

timsOmni Sigma uses managed electronic dissociation and Omnitrap for sequential enrichment and MSn analysis. The combination of TIMS and PASEF-EXD helps to link PTM, conformation and biological function.

Supported by CCS, collision-induced unfolding, trapped eXd and all PASEF modes, the regulated energy of electrons covers ECD 0–2 eV, EXD 12–17 eV and EID 35 eV; the precursor consumption in trapped eXd can exceed 90%.

Key figures

Applications

• Glycoproteomics
• Structural biology
• Analysis of post-translational modifications
• Collision-induced unfolding
• multiOmics

Models and configurations

• timsOmni Sigma

Product details

Electronic dissociation

• The regulated energy of electrons covers ECD (0–2 eV), EXD (12–17 eV) and EID (35 eV)
• Trapped eXd can consume more than 90% of the precursor

Separation and analysis

• CCS measurement, collision-induced unfolding and all PASEF modes are supported
• Omnitrap links data on posttranslational modification, conformation and biological function

Technology

Related equipment types

• Protein sampling systems
• Nano-HPLC systems
• Immunoaffinity enrichment

Classification

• Toxicology and omics
• Proteomics
• Analytical instruments for biological samples
• Mass spectrometry
• Q-TOF and ionic mobility (timsTOF): proteomics, metabolomics
• TIMSOMNI SIGMA Mass Spectrometer

Product images

Documents

• timsOmni family brochure

Manufacturer sources

• timsOmni Sigma official page
• timsOmni family brochure
• timsOmni Sigma official page
• timsTOF portfolio
• PASEF technology