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SKYSCAN 1276 CMOS Edition

Bruker

SKYSCAN 1276 CMOS Edition

Lifetime 3D visualization of small animals with a resolution of up to 6 microns on a desktop appliance

High-performance desktop micro-CT for longitudinal in vivo studies and detailed ex vivo imaging.

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SKYSCAN 1276 performs non-destructive three-dimensional examination of small laboratory animals and biological samples. The system supports continuous and step-by-step scanning, variable magnification, physiological monitoring and synchronization with breathing or ECG; complete software is used for reconstruction, alignment and reconstitution. Quantitative analysis of data.

The minimum pixel size is 2.8 μm, the distinguishable part is 6 μm with a contrast of more than 10%. The scanning area reaches 75 mm in diameter and 310 mm in length, the total volume of one scan is up to 7 800 × 7 800 × 2 500 voxels. The manufacturer's materials stated the fast scan time of 3.9 s and 16 megapixel CMOS detector.

Resolution and speed

  • The 16-megapixel sCMOS detector with extended field of view and increased sensitivity reduces scan time by up to two times compared to the previous generation.
  • Native image resolution up to 7,800×7,800 pixels per slice allows you to zoom in on any section of the 3D volume without re-scanning.
  • Clean Image mode reduces typical CT artifacts already in the shooting stage, without additional post-processing

Lifetime visualization of animals

  • Interchangeable multimodal cassettes for animals with anesthesia mask, ECG electrodes and temperature sensor, a single connector for fast connection
  • Built-in physiological monitoring: 5 MP video surveillance with real-time motion detection, ECG, breathing, temperature stabilization
  • Real-time screen dosimeter; patented low-dose filter reduces dose by 2-3 times without loss of image quality

3D.SUITE Software

  • NRECON – reconstruction of 2D projections in 3D volume with GPU acceleration, up to 10 times faster than CPU reconstruction; support for circular and spiral shooting
  • DataViewer, CTVox, CTAn and CTVol – post-slice viewing, volume rendering, quantitative analysis and surface modeling with export to STL
  • GLP with three levels of user rights to meet good laboratory practice requirements

Source and detector

ParameterSKYSCAN 1276 CMOS Edition
X-ray source40–100 kV, 20 W, focal spot <5 μm at 4 W
DetectorsCMOS, 16 MP, 4,096×4,096 pixels

Scanning resolution and volume

ParameterSKYSCAN 1276 CMOS Edition
Minimum pixel size2.8 μm
Distinguished detail (contrast >10%)6 μm
Image format after one scanup to 7,800×7,800×2,500 Voxels
Scanning areaup to 75 mm in diameter, up to 310 mm in length

Security and monitoring

ParameterSKYSCAN 1276 CMOS Edition
Radiation protection<1 μSv/h on the surface of the instrument
Physiological monitoring5 MP video, ECG, breathing, temperature; digitization of 16 bits, up to 120 counts / s

Dimensions and connection

ParameterSKYSCAN 1276 CMOS Edition
Mass/size360 kg / 954×1190×940 mm
Power supplysingle-phase household network, without water cooling

Model range

ParameterSKYSCAN 1276 CMOS Edition
The Skyscan lineup also includesSKYSCAN 2214 - X-ray microscope for analysis of biological samples at nanoresolution; X4 POSEIDON - modular desktop platform for ex vivo X-ray imaging with micron resolution