Micro Solutions / Life Science

PMOD Software Package for Quantitative Image Analysis

Modular environment for quantitative analysis of PET, SPECT, CT and MRI – from kinetics to segmentation

Product overview

PMOD
Bruker
USA
ParaVision / PMOD / AutoPac
PMOD

Modular environment for quantitative analysis of PET, SPECT, CT and MRI – from kinetics to segmentation

tools for neurology, cardiology, oncology and preclinical research, RUO

Modular software environment for quantitative analysis of PET, SPECT, CT and MRI data.

pmod combines image registration and fusion, SUV and %ID/cc, kinetic modeling, parametric maps, segmentation, neuro- and cardio analysis, 3D imaging and data management. Tools support small animals, humans and multimodal research.

PKIN contains more than 50 configurations of kinetic models, PXMOD more than 30 blood and reference-tissue models, and the built-in SDMS provides centralized project storage and reproducible batch processes. Analysis in 2D/3D/4D, rigid/deformable registration and modular licenses are available.

Key figures

11

specialized modules

>50

Model configurations in PKIN

>30

modelling

RUO

scientifically only

Applications

Kinetic modelling of PET
Brain analysis (PET/MRI)
Cardiac imaging
Oncological segmentation
Multimodal image registration

Models and configurations

PMOD

Product details

PBAS

Image processing and VOI analysis

PFUS

imaging

PKIN

kinetic modeling

Modular architecture

PBAS is a mandatory basic viewing, image processing and VOI analysis module for any PMOD configuration.
A set of specialized modules is selected for the tasks of the laboratory: from general kinetics to highly specialized applications in neurology, cardiology and oncology.
Interface to R statistical package directly from PBAS for additional statistical calculations

Kinetic modelling

PKIN is a palette of more than 50 configurations of kinetic models, including blood models and tri-exponential/Hill functions for metabolite correction; used by researchers for more than 15 years.
PXMOD – pixel parametric mapping, over 30 blood models and reference-tissue approaches, with the results transmitted back to the interactive PKIN
Monte-Carlo simulations to assess the reliability of simulation parameters

Specialized annexes

PNEURO – Automated PET/MRI brain analysis with Hammers atlas (N30R83) for humans and separate atlases for rat, mouse, pig and Javanese macaque
PALZ – fully automatic discrimination analysis of Alzheimer’s disease by FDG-PET brain
PSEG - segmentation of cancer centers with the calculation of SUVmean, SUVpeak, SUVmax, MTV, sphericity and largest diameter
PCARD/PCARDP – Quantitative assessment of the heart according to PET and MRI data based on PKIN

Core modules

Image processing and VOI analysis	PBAS – basic mandatory module
General kinetic modelling	PKIN – more than 50 model configurations
Pixel parametric mapping	PXMOD – More than 30 models
Image registration and merging	PFUS
3D visualization	P3D
Geometric Models and Simulation	PGEM

Specialized modules

Brain analysis (PET/MRI)	PNEURO - Hammers N30R83 atlas (human); atlases for rat, mouse, pig, Javanese macaque
Analysis of Alzheimer's disease	PALZ – Automatic Discriminatory Analysis for FDG-PET
Segmentation of cancer foci	PSEG
Cardiology	PCARD / PCARDP

System Requirements (for PNEURO)

Operating system	64-bit
RAM	at least 32 GB
Processor	at least 8 cores (4 cores for PBAS configuration)

Purpose

Status of application	Research only (RUO); not diagnostics or treatment of patients
Data formats	Import/export of medical images, compatibility with research databases (SDMS)

Additional licenses

ATL (Audit Trail License)

Client-server audit trail module to comply with FDA 21 CFR Part 11 requirements for clinical trial image processing

Related equipment types

Preclinical MRI systems (BioSpec)
Hybrid PET/CT and PET/MR systems
Desktop Micro-CT (SKYSCAN)
Visualization Management (ParaVision 360)

Classification

Scientific and production equipment
Preclinical imaging software
Microscopy and imaging systems
Image analysis and morphometry
PMOD