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Modular PET/SPECT/CT system of the CUBES series

Bruker

Modular PET/SPECT/CT system of the CUBES series

Desktop platform for preclinical imaging: from one modality to a complete PET/SPECT/CT complex

CUBES Modular Series for Compact Preclinical PET, SPECT and CT Visualization on the Laboratory Desk.

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β-CUBE, γ-CUBE and X-CUBE allow you to start with a separate modality and combine modules into a multimodal process. The systems are designed to study mice and rats, support automated positioning, and generate combined anatomical and molecular data.

The line includes individual PET, SPECT and CT modules with wireless control and CUBEFLOW software process. The exact spatial resolution, field of view, sensitivity and set of collimators depend on the selected module and configuration; they are not unified in the group card.

Modularity

  • Three independent modules – β-CUBE (PET), γ-CUBE (SPECT) and X-CUBE (CT) – can be purchased and installed separately or combined into a multimodal complex.
  • CUBEFLOW’s shared platform manages all modules from a single workplace or microplate: study planning, data collection, reconstruction and monitoring of an animal.
  • Compact tabletop formogabarite (about 54×56 cm in plan) saves the area of the laboratory

Detection technologies

  • β-CUBE uses digital SiPM/LYSO PET detectors with full DOI resolution in depth interaction
  • γ-CUBE is built on SiPM/NaI(Tl) detectors with patented ultra-high resolution collimators and support for multiisotope research.
  • X-CUBE provides low-dose CT imaging with cardio and respiratory gateway

Throughput

  • β-CUBE: static and dynamic shooting of up to 4 mice at a time, support cardiostating
  • γ-CUBE: static and dynamic shooting of up to 3 mice at a time
  • X-CUBE: Low-dose shooting of up to 4 mice at a time

β-CUBE - PET

Parameterβ-CUBE (PET)γ-CUBE (SPECT)X-CUBE (CT)
Spatial resolution850 μm
Sensitivity>12%
Field of view (transaxial/axial)72 mm / >250 mm
DetectorSiPM/LYSO, digital, with DOI resolution
Mass/dimension~90 kg / 54×56×54 cm

γ-CUBE - SPECT

Parameterβ-CUBE (PET)γ-CUBE (SPECT)X-CUBE (CT)
Spatial resolution500 μm
Sensitivity>1,2%
Field of view (transaxial/axial)up to 60 mm / > 250 mm
Energy rangeup to 511 keV, energy resolution <10%
DetectorSiPM/NaI(Tl), ultra-lofthole collimators
Mass/dimension~130 kg / 54×56×54 cm

X-CUBE - CT

Parameterβ-CUBE (PET)γ-CUBE (SPECT)X-CUBE (CT)
Spatial resolution50 μm
Field of view (transaxial/axial)65 mm / >250 mm
Gentry diameter86 mm
Source energy range20-50 keV
Mass/dimension~120 kg / 54×56×71 cm

Software

Parameterβ-CUBE (PET)γ-CUBE (SPECT)X-CUBE (CT)
Management platformCUBEFLOW: Planning, collection, reconstruction, animal monitoring, automatic quality control
Interface.single workspace or microplate for all modules