600
samples/hour
Micro Solutions / Life Science
MALDI-TOF Biotyper Sirius
Microorganism identification in minutes: up to 600 samples per hour
Product overview
- MALDI Biotyper sirius
- Bruker
- Germany
- MALDI Biotyper
- MALDI Biotyper sirius
Microorganism identification in minutes: up to 600 samples per hour
Positive and Negative Ion Regime for Routine and Research
High-performance MALDI-TOF system for rapid identification of microorganisms in clinical microbiology.
The system maps the mass-spectral profile of the isolate to the MALDI Biotyper library. IDealTune's automatic setup, long-lasting smartbeam laser and MBT Compass software environment support a standardized flow from target to result.
The manufacturer claims performance up to 600 samples per hour and the weight of the device is 75 kg. the Sirius version supports measurements in positive and negative ion modes; negative mode is intended for research applications.
Key figures
~5 minutes
Report on the 96-position target
>4 600
library
CE-IVD
ivD
Applications
- Clinical microbiology
- Identification of bacteria and yeast
- Mycelial mushrooms and mycobacteria
- Identification from hemocultures
- Early detection of resistance
- Lipid studies (negative regimen, RUO)
Models and configurations
- MALDI Biotyper sirius
Product details
MALDI-TOF Desktop System
75 kg, rapid target change
Expendables IVD
Targets, HCCA matrix, BTS test standard
Speed
- Results appear on the screen as the spectra are shot, without waiting for the end of the run.
- The full target (95 isolates and control) is processed in about 5 minutes.
- Urgent samples can be prioritized and answered in minutes.
- Smart Spectra Acquisition reduces the number of laser shots per sample
Opportunities
- Two ionic modes: positive for routine identification, negative for research tasks, such as lipid analysis
- The library covers Gram-positive and Gram-negative bacteria, yeast and mycelial fungi
- Modules for hemocultures, mycobacteria, fungi and markers of resistance
Ease of operation
- IDealTune auto-tuning performed in the background when analyzing the test standard
- Cleaning of the ion source is started from the software without depressurization
- Results in a clear “traffic light” color scheme
- Smartbeam laser with a life of 7 years or 500 million shots
Throughput
| Throughput | up to 600 samples/h |
|---|---|
| Full target report (95 isolates + 1 QC) | ~5 minutes |
| Sample preparation, manual time | ~20 s per isolate; 95 isolates less than 20 min |
| Direct identification from positive hemoculture | 15-20 minutes after the signal (Rapid Sepsityper Workflow) |
Mass spectrometer
| Method | MALDI-TOF mass spectrometry, desktop system |
|---|---|
| Ion regimen | Positive; negative (for research purposes only, RUO) |
| laser | Smartbeam, 200 Hz, resource 7 years or 500 million shots |
| Setting up | Automatic IDealTune with IVD Bacterial Test Standard |
| Cleaning up the ion source | built-in, IR laser, without vacuum disturbance |
| Weight | 75 kg |
Library and software
| Software | MBT Compass HT IVD with MBT IVD Library |
|---|---|
| Library coverage | More than 4,600 species/groups of bacteria, yeasts and mycelial fungi |
| Targets | MBT Biotarget 96 IVD, 96 positions, barcode |
| Integration | LIS/LIS, Sensitivity Determination Systems (AST), Laboratory Automation Systems |
Expendables IVD
MBT Biotarget 96 IVD
Disposable targets for 96 positions with an individual barcode, a set of 20 pieces.
IVD HCCA Matrix, portioned
Positioned matrix HCCA: 10 tubes of 250 μl
IVD Bacterial Test Standard (BTS)
Standard for quality control and operation of IDealTune: 5 tubes of 50 μl
MSP adapter for MBT Biotarget 96
Adapter for installing disposable targets in the device
Extended task kits
MBT Sepsityper IVD Kit
Isolation of microorganisms from 50 positive hemocultures
MBT Mycobacteria IVD Kit
Safe inactivation and sample preparation of mycobacteria from liquid and dense media
MBT STAR-Carba IVD Kit / MBT STAR-Cepha IVD Kit
Phenotypic detection of carbapenemasic and cephalosporinasic activity
MBT Compass HT IVD Software Modules
MBT HT Sepsityper IVD Module
Identification directly from positive hemoculture
MBT HT Mycobacteria IVD Module
Identification of Mycobacterium spp.
MBT HT Filamentous Fungi IVD Module
Identification of mycelial fungi with a separate library
MBT HT Subtyping IVD Module
Differentiation of hard-to-detect species and resistance markers (blaKPC, cfiA)
MBT HT STAR-BL IVD Module
Support for MBT STAR-Carba and STAR-Cepha assays
Optimization and automation
MBT Shuttle
Non-slip holder of the target, matrix and tubes BTS during sample preparation
MBT FAST Shuttle IVD
Standardized accelerated drying of matrix and liquid reagents
MBT Pilot System
Illumination of the next free position of the target when applying samples
Related equipment types
- Automatic systems for determining antibiotic sensitivity
- Hemocultural analyzers
- Biosafety cabinets
- LIS for microbiology
Related products
- Xian Tianlong GeneFlex — Automatic systems for determining antibiotic sensitivity
- Miralab SpermoLyzer — Hemocultural analyzers
- Heal Force HFsafe 900 — Biosafety cabinets
Classification
- Microbiology
- MALDI-TOF Identification
- Microbiological equipment
- Identification and sensitivity determination
- MALDI-TOF System for Identification of Microorganisms
- MALDI Biotyper sirius