>60 000
permission
Micro Solutions / Life Science
QTOF High-resolution Impact II VIP Mass Spectrometer
Resolution of over 60,000 at full sensitivity and 1 ppm mass accuracy for screening and metabolomics
Product overview
- impact II VIP
- Bruker
- USA
- qTOF
- impact II VIP
Resolution of over 60,000 at full sensitivity and 1 ppm mass accuracy for screening and metabolomics
dual-source VIP-HESI/APCI and paired with UHPLC, GC, CE and IC
QTOF is a high-resolution mass spectrometer for trace analysis in complex matrices: exact mass, sensitive MS/MS and a wide dynamic range in a single instrument.
The VIP II impact simultaneously addresses screening, identification and quantification tasks, from pesticide residues and PFAS to forensic toxicology and metabolomics, and interfaces with UHPLC, GC, CE and IC, and works with DART, GC-APCI and APPI sources.
Full sensitivity resolution exceeds 60,000, mass accuracy is 1 ppm in automatic calibration. 50 Gbps digitization provides intraspectral dynamic range of more than 5 orders of magnitude. Double source VIP-HESI/APCI increases the efficiency of ionization of thermolabile compounds.
Key figures
1 ppm
mass-precision
>5 orders of magnitude
range
50 Gbps
digitization
Applications
- Metabolomics and biomarker search
- Pesticide residues and pollutants
- Forensic toxicology
- PFAS in water
- Authenticity of food products
Models and configurations
- impact II VIP
Product details
impact II VIP
QTOF High-resolution QTOF
SOURCE VIP-HESI
vacuum insulation protects the eluent from overheating
Accuracy and dynamic range
- Resolution of over 60,000 without loss of sensitivity
- Accuracy of mass of 1 ppm in automatic calibration
- Intraspectral dynamic range of more than 5 orders of magnitude thanks to 50 Gbps digitization
Stability for large series
- 300 NIST SRM 3672 urine injections: median RSD peak area 9.56% without normalization
- Double-ion funnel and Active Exhaust reduce pollution and maintenance
- MCP detector without long-life scintillator
Sensitivity in routine
- PFOA, PFHxS and PFBS at 1 ng/L in drinking water at RSD <5%
- 294 pesticides in wheat in 5 minutes
- DART: 384-hole microplate in less than 25 minutes
Mass analyzer
| Type | Quadrupole - Time-of-flight (QTOF) |
|---|---|
| Full Sensitivity Resolution (FSR) | > 60 000 |
| Mass accuracy | 1 ppm (automatic calibration) |
| Dynamic range | > 5 orders (intraspectral) |
| Digitization | 50 Gbps, 10-bit digitizer |
| Detector | MCP, no scintillator |
Ionization and conjugation
| Sources | VIP-HESI/APCI; optionally DART, GC-APCI II, APPI II, CaptiveSpray 2 |
|---|---|
| Pairing. | UHPLC, GC, CE, IC |
Software
| Processing | TASQ (with RealTimeQC), MetaboScape, TargetScreener HR |
|---|
Status
| Purpose | RUO – for research purposes only |
|---|
Sources of ionization
DART
Analysis of solid, liquid and gaseous samples without chromatography
GC-APCI II
Pairing with GH through heated transfer line with the delivery of calibration
APPI II
Photoionization of small-polar and non-polar molecules
CaptiveSpray 2
Nanoflow source for proteomics
Software and libraries
TargetScreener HR
Targeted and non-targeted screening for more than 3,000 compounds
MetaboScape
Statistics, annotation and identification of unknowns
NIST/EPA/NIH Mass Spectral Library 2023
Search by spectral library
Related equipment types
- HPLC/UHPLC systems
- Gas chromatographs
- Nitrogen generators
- Water treatment systems
Related products
- BUCHI Pure Excellence C-915 — Gas chromatographs
- Young In Chromass aquapuri Essence — Water treatment systems
Classification
- Toxicology and omics
- Metabolomics
- Analytical instruments for biological samples
- Mass spectrometry
- Q-TOF and ionic mobility (timsTOF): proteomics, metabolomics
- QTOF High-resolution Impact II VIP Mass Spectrometer