600 MHz
NMR frequency
Micro Solutions / Life Science
NMR platform AVANCE IVDr
Automated 600 MHz NMR analysis of bioliquids for metabolomic research
Product overview
- Avance IVDr
- Bruker
- Germany
- Avance IVDr
- Avance IVDr
Automated 600 MHz NMR analysis of bioliquids for metabolomic research
Standardized Platform for Biobanking and Clinical Research (RUO)
A standardized automated 600 MHz NMR platform for metabolomic bioliquid research.
AVANCE IVDr combines a high-field NMR spectrometer, temperature-controlled SampleJet, barcoding, LIMS, validated SOP and automatic analysis. One non-destructive measurement supports quantitative profiling of metabolites, lipoproteins and sample quality control.
The platform operates at 600 MHz proton frequencies and supports urine, plasma/serum, CSF and methanol extracts. The biobanking suite lists 114 lipoprotein profile parameters and 41 small plasma/serum molecules, as well as 150 urine parameters. application.
Key figures
114
parameterizes lipoproteins
150
urine-parameter
RUO
research-only
Applications
- Metabolomics of bioliquids
- Lipoprotein plasma/serum profile
- Quality control of biobank samples
- Epidemiological studies
- Urine profiling
Models and configurations
- AVANCE IVDr
Product details
Platform AVANCE IVDr
Automated NMR analysis of bioliquids
Automatic analysis report
Example of the B.I.-LISA report
Automation and standardization
- The B.I.-Methods 2.0 kit includes validated SOP sample preparations for urine, plasma/serum, CSF and methanol extracts
- QuantRefManager as part of TopSpin software manages the quantitative calibration of the system
- IconNMR software is automatically configured to meet the requirements of the IVDr platform
- IVDr Data Browser simplifies the management of spectra and metadata samples
Analytical capabilities
- One nondestructive measurement gives a lipoprotein profile (114 parameters) and a list of 41 small plasma/serum molecules.
- The urine profile includes 150 quantitative parameters with concentration ranges.
- Capacity of up to 150 samples per day in screening mode
Quality and reproducibility
- Sample quality control and spectrum impurities detection (B.I.BioBankQC report)
- Identical reproducibility of spectra between instruments and laboratories with a single SOP is shown
Spectrometer
| Frequency of NMR | 600 MHz |
|---|---|
| Types of specimens | urine, plasma/serum, CSF, methanol extract |
| Diameter of the tubes | 3 mm and 5 mm |
Analytical panels
| Lipoprotein Profile (B.I.-LISA) | 114 parameters |
|---|---|
| Small plasma/serum molecules (B.I.QUANT-PS 2.0) | 41 parameters |
| Urine parameters (B.I.QUANT-UR) | 150 parameters |
| Screening capacity | up to 150 samples per day |
Software
| Software | TopSpin, IconNMR, QuantRefManager, IVDr Data Browser, SampleTrack |
|---|---|
| Standardization module | B.I.-Methods 2.0 |
Software and analysis modules
B.I.-LISA
Analysis of lipoprotein plasma/serum subclasses
B.I.QUANT-PS 2.0
Quantitative analysis of small plasma/serum molecules
B.I.QUANT-UR
Quantitative analysis of endogenous urine metabolites
B.I.BioBankQC
Quality control of biobank samples
Related equipment types
- Centrifuges
- Sample sampling systems
- Data analysis software
Related products
- Cence TG16-WS — Centrifuges
Classification
- Toxicology and omics
- Metabolomics and lipidomics by NMR method
- Analytical instruments for biological samples
- NMR spectroscopy of biosamples
- Avance IVDr