300x
speed-up
Micro Solutions / Life Science
Accelerator of bioinformatics analysis MegaBOLT
Hardware acceleration of WGS/WES analysis: up to 300 times faster than the classical algorithm
Product overview
- MegaBOLT
- BGI
- China
- ZTRON / MegaBOLT
- MegaBOLT
Hardware acceleration of WGS/WES analysis: up to 300 times faster than the classical algorithm
MegaBOLT, ZBOLT and ZBOLT Pro range – from workstation to rack servers
BGI MegaBOLT is a specialized accelerator for secondary analysis of NGS data for a quick transition from FASTQ to variants and applied results.
The hardware and software platform accelerates WGS/WES conveyors, standardizes resource-intensive alignment and call stages of variants, and is available in a workstation or server series format.
The family includes the MegaBOLT workstation and the ZBOLT/ZBOLT Pro racks. Entire genome analysis, exome and specialized piplins are supported; actual performance depends on the hardware configuration version, the number of parallel tasks, and the workflow selected.
Key figures
3
lineage
Applications
- Full-genome sequencing analysis (WGS)
- Exome analysis (WES)
- Panel sequencing
- Geminal and somatic options
Models and configurations
- MegaBOLT
- ZBOLT
- ZBOLT Pro
Product details
MegaBOLT/ZBOLT line
hardware acceleration of bioinformatics analysis
Speed
- Accelerates typical WGS/WES/panel analysis pipelines up to 300 times compared to the classical algorithm
- The germinal WGS 30× (Basic) is performed in 1.50 hours on MegaBOLT instead of 42.82 hours by the classical method.
- Somatic analysis of WGS 40×/40× fits in 5.17 hours on MegaBOLT vs. 58.20 hours classically
Line of executions
- MegaBOLT – a desktop workstation for moderate-load laboratories
- ZBOLT and ZBOLT Pro – rack servers for higher bandwidth
- Supported germinal and somatic options according to WGS, WES and targeted panels
Analysis time - germinal options
| Germline WGS 30×Basic (classic 42.82 h) | 1.50 hp 0.52 hours 0.12 hours |
|---|---|
| Germline WGS 30×Full (classic 44.00 h) | 1.94 hours 0.64 hours 0.16 hours |
| Germline WES 100×Basic (classic 4.9 h) | 0.26 hours 0.09 hp 0.02 hours |
| Germline WES 100×Full (classic 5.04 h) | 0.32 hours 0.11 hp 0.03 hp |
Analysis time - somatic options
| Somatic WGS 40× Tumor + 40× Normal (classically 58.20 hours) | 5.17 hours 1.74 h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h h 0.44 hours |
|---|---|
| Somatic WES 400× Tumor + 400× Normal (classically 9.53 hours) | 0.86 hours 0.29 hours 0.07 hhr |
Architecture and execution
| Form factor | workstation rack-server rack-server |
|---|---|
| Acceleration method | multithreaded hardware system for accelerating bioinformatics analysis |
Related equipment types
- DNBSEQ sequencing
- Genomic Data Storage Platforms (ZTRON)
- Bioinformatics analysis
Related products
- BGI DNBSEQ-E25 — DNBSEQ sequencing
- BGI ZTRON — Bioinformatics analysis
Classification
- Sequencing and genotyping
- Bioinformatics and data management
- Equipment for molecular biology and genetics
- Bioinformatics and software
- Analysis and interpretation of NGS data
- MegaBOLT