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Micro Solutions / Life Science
Digital platform of IHH and CISH: quantitative assessment of ER, PR, HER2, Ki-67, P53 and PD-L1 with zoom up to 80×
Digital platform of IHH and CISH: quantitative assessment of ER, PR, HER2, Ki-67, P53 and PD-L1 with zoom up to 80×
open platform for light-field microscopy, multiplex color matching
ASI HiPath Pro is an open digital platform for viewing and quantifying light-field histological images, including standardized IHC and CISH assessments.
HiPath Pro provides scanning or import of whole slides, navigation with digital magnification up to 80×, marking, joint matching of several stains and automatic transfer of areas of interest. Computer classifiers perform the quantification of nuclear and membrane markers, including ER, PR, HER2, Ki-67, P53 and PD-L1, and In situ chromogenic hybridization: ASI images and compatible third-party scanners are supported.
The platform is available as a manual station on one slide, a system on 9 slides or a loader on 99 slides. Automated configurations use Olympus BX63 BF or ZEISS Axio Imager Z2 BF and a color CMOS camera 5 MP; for a 9-slide system, dimensions are 61 × 69 × 85 cm and a weight of 45 kg, for a 99-slide system – 100 × 90 × 90 cm and 80 kg. The equipment, lenses, scanning and analytical modules are selected according to the laboratory workflow.
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Markers: ER, PR, HER2, Ki-67, P53, PD-L1
HER2, ER, PR, Ki-67 - Manual configuration
numerical
ER, PR, HER2, Ki-67
scan, analysis, report
| Configuration. | hand station (1 slide), 9-slide system, 99-slide loader |
|---|---|
| Microscope | Olympus BX63 BF or ZEISS Axio Imager Z2 BF (automated configurations) |
| Camera. | 5MP CMOS, colored |
| Digital zoom | up to 80x |
| Barcode reader | 1D/2D handmade (1 and 9 slides); built-in 1D/2D (99 slides) |
| System with 9 slides | 61 x 69 x 85 cm, 45 kg |
|---|---|
| 99-slide system | 100 x 90 x 90 cm, 80 kg |
| Markers | ER, PR, HER2, Ki-67, P53, PD-L1 and others |
|---|---|
| Method | Quantitative scoring of nuclear and membrane markers, CISH assessment |
| Regulatory status | FDA-permission for HiPath IHC Family (HER2, ER, PR, Ki-67) on manual configuration |
Automatic midstream scan, optional oil autodoser
Fully automated large flow scanning with built-in barcode reader and auto-supply oil